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LUNG TRANSPLANT AND HEART-LUNG TRANSPLANT
Lung Transplantation is a surgery used to replace
diseased lungs or heart with a healthy heart and lungs
from a human donor. Types of surgery include:
single-lung transplantation, double-lung
transplantation, heart-lung transplantation.
Lung transplant operations have been performed since
1980 in the United States. The heart and lungs are
usually donated from a human who has been declared
brainstem-dead yet remains on life-support. Tissue
matches are made to match a patient and donor to
minimise the risk of the patient rejecting the
transplanted lung or heart.
The patient is placed under general anesthesia and an
incision is made through the breast bone (sternum). At
the same time tubes re-route the blood to a special
heart-lung bypass machine that keeps the blood
oxygenated and circulating during the surgery. The
patient's heart and/or lungs are removed and the donor
heart and lungs are stitched into place.
Heart-lung transplant may be recommended for patients
with severely diseased lungs such as primary pulmonary
hypertension or a severely damaged heart which occurs in
severe cases of pulmonary hypertension.
The lungs work to bring air in contact with blood so
that oxygen can be introduced into the body and carbon
dioxide removed. The lungs are two cone shaped, spongy
organs inside the chest cavity. Lungs lie from
the bottom of chest to a point above the collar bone and
they lie against ribs.
Having a single lung transplant means having an
operation to remove one of diseased lungs and replacing
it with a new lung. Having a double lung transplant
means having an operation to remove both of diseased
lungs. These lungs are replaced with the healthy lungs
from another human being. This new lung(s) will
work to help breathe by providing body with oxygen and
removing carbon dioxide just as own lungs did when they
were healthy. This new lung or lungs will come from
a person who is an organ donor. This person has
suffered and injury to the blood supply to the brain
which results in "brainstem death". This person's lungs
are normal and not affected by this injury.
A lung transplant generally prolongs the life of a
patient who otherwise would die because of advanced
stage PPH. A transplant is performed only in patients
where there is a very good chance of success. According
to the United network for Organ Sharing (UNOS) the
patient survival rates for all patients that had a lung
transplant are 85% at one month, 69% at one year, and 51
% at three years for patients transplanted between 1987
and 1992. Results since those years are likely to be
much better.
After the surgery the body may reject the organs. The
body's immune system may consider the transplanted
organs an invader and rejects the organs the same way it
would fight an infection. To stop the body from
reacting in this way, organ transplant patients are
given anti-rejection (immunosuppression) drugs (such as
cyclosporine and corticosteroids) that suppress the
body's immune response and reduce the chance of
rejection. Sorry to state that these drugs also reduce
the body's natural ability to fight off other dangerous
infections.
A patient undergoing a lung transplant will often remain
in the hospital for months, that full recovery period is
about 6 months. Follow-ups along with blood tests and
X-ray will be necessary for the remainder of the
patients life. |